Reactions

Silver precatalyst for the asymmetric allylation of aldehydes Silver catalyst for intramolecular additions of alcohols and carboxylic acids to inert olefins Silver catalyst for the fluorination of boronic acids Silver catalyst for the fluorination of functionalized aryl stannanes Silver catalyst for cyclopropenation of internal alkynes with donor/acceptor substituted diazo compounds Silver catalyst for the reaction of 2-alkynylbenzaldehyde with 2-isocyanoacetate

Purification Methods

Recrystallise it twice from hot CCl4 [Alo et al. J Chem Soc, Perkin Trans 1 805 1986]. Store it in the dark. [Beilstein 3 IV 34.]

General Description

Silver trifluoromethanesulfonate (AgOTf) is a versatile silver(I) salt commonly used as a cocatalyst or activator in transition metal-catalyzed reactions, particularly in gold(I)- and rhodium(I)-catalyzed processes. It facilitates the generation of cationic metal species, enhancing reactivity in cycloadditions, hydroarylations, and annulation reactions. AgOTf is also employed in glycosidation and other synthetic transformations, demonstrating its utility in forming complex organic structures, though its role may vary depending on the reaction system and conditions.