Peramivir
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Product Name :
Peramivir
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CAS No :
229614-55-5
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Project State :
Commercial
Application
General Description
Good factory supply good Peramivir 229614-55-5
- Molecular Formula:C15H28N4O4
- Molecular Weight:328.412
- Refractive Index:1.613
- PSA：148.53000
- Density:1.39g/cm3
- LogP:1.44240
Peramivir(Cas 229614-55-5) Usage
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Pharmaceutical Applications |
An intravenously administered neuraminidase inhibitor currently under investigation for the treatment of influenza infections in normal and high-risk patient populations. No drug interactions of note have yet been identified. |
InChI:InChI=1/C15H28N4O4/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19)/t9-,10+,11+,12-,13+/m0/s1
229614-55-5 Relevant articles
Facile synthesis of the neuraminidase inhibitor peramivir
Jia, Fei,Hong, Juan,Sun, Ping-Hua,Chen, Jian-Xin,Chen, Wei-Min
, p. 2641 - 2647 (2013/07/26)
An improved and convenient synthetic rou...
A NOVEL PROCESS FOR THE PREPARATION OF PERAMIVIR AND INTERMEDIATES THEREOF
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Page/Page column 28-29, (2012/11/13)
The present invention relates to a novel...
(1S, 2S, 3S, 4R)-3-Y(1S)-1-ACETYLAMINO-2-ETHYL-BUTYL¨-4-GUANIDINO-2- HYDROXYL-CYCLOPENTYL-1-CARBOXYLIC ACID HYDRATES AND PHARMACEUTICAL USES THEREOF
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Page/Page column 6; 12-13, (2010/06/15)
The present invention relates to (1S,2S,...
229614-55-5 Process route
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![(-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-({[(tert-butoxycarbonyl)amino][(tert-butoxycarbonyl)-imino]methyl}amino)-2-hydroxycyclopentanecarboxylic Acid](/upload/2025/9/c43e3501-958f-4b8f-860f-ad6ceec6726d.png)
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383910-27-8
(-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-({[(tert-butoxycarbonyl)amino][(tert-butoxycarbonyl)-imino]methyl}amino)-2-hydroxycyclopentanecarboxylic Acid
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229614-55-5,229614-56-6
peramivir
| Conditions | Yield |
|---|---|
|
(-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-({[(tert-butoxycarbonyl)amino][(tert-butoxycarbonyl)-imino]methyl}amino)-2-hydroxycyclopentanecarboxylic Acid;
With
hydrogenchloride;
In
water;
at 0 ℃;
With
sodium hydroxide;
In
water;
pH=6 - 7;
|
73% |
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1116682-13-3
C14H25N2O4(1-)*Na(1+)
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1H-1,2,4-triazole-1-carboximidamide monohydrochloride
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-
229614-55-5,229614-56-6
peramivir
| Conditions | Yield |
|---|---|
|
C14H25N2O4(1-)*Na(1+); 1H-1,2,4-triazole-1-carboximidamide monohydrochloride;
In
water;
for 1h;
Industry scale;
With
sodium hydroxide;
In
water;
at 20 ℃;
pH=8.4;
|
229614-55-5 Upstream products
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1116682-13-3
C14H25N2O4(1-)*Na(1+)
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97-96-1
2-Ethylbutyraldehyde
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383910-27-8
(-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-({[(tert-butoxycarbonyl)amino][(tert-butoxycarbonyl)-imino]methyl}amino)-2-hydroxycyclopentanecarboxylic Acid
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1404223-97-7
(1S,4R)-methyl-4-(2,3-bis(tert-butoxycarbonyl)guanidino)cyclopent-2-ene-carboxylate