Pharmaceutial Intermediates
  • DIMETHYL VINYLPHOSPHONATE

    • Product Name   :   

      DIMETHYL VINYLPHOSPHONATE

    • CAS No   :   

      4645-32-3

    • Project State   :   

      Commercial

    Application

    General Description

    Cost-effective and customizable DIMETHYL VINYLPHOSPHONATE 4645-32-3 supplier

    • Molecular Formula:C4H9 O3 P
    • Molecular Weight:136.087
    • Vapor Pressure:3.83mmHg at 25°C 
    • Melting Point:<-30°C 
    • Refractive Index:n20/D 1.428 
    • Boiling Point:197-202 °C(lit.)  
    • Flash Point:101°C 
    • PSA:45.34000 
    • Density:1.146 g/mL at 20 °C(lit.)  
    • LogP:1.61580 

    DIMETHYL VINYLPHOSPHONATE(Cas 4645-32-3) Usage

    General Description

    Dimethyl vinylphosphonate is a chemical compound with the formula C5H9O3P, with a molecular weight of 146.09 g/mol. It is a colorless liquid with a fruity odor and is highly flammable. Dimethyl vinylphosphonate is commonly used as a monomer in the production of polymers and copolymers for various applications, including flame retardants, adhesives, and coatings. It is also used in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Furthermore, dimethyl vinylphosphonate is known to react readily with nucleophiles, such as amines, alcohols, and thiols, making it a versatile building block in organic synthesis. However, it is important to handle dimethyl vinylphosphonate with care, as it is toxic and can cause skin and eye irritation upon contact.

    InChI:InChI=1/C4H9O3P/c1-4-8(5,6-2)7-3/h4H,1H2,2-3H3

    4645-32-3 Relevant articles

    -

    Callot,H.J.,Benezra,C.

    , p. 3382 - 3387 (1970)

    -

    METHOD FOR PRODUCING ALKENYLPHOSPHORUS COMPOUND

    -

    Paragraph 0068-0074, (2021/06/04)

    PROBLEM TO BE SOLVED: To provide a metho...

    Method for synthesizing allyl phosphonic acid derivative (by machine translation)

    -

    Paragraph 0041-0145, (2020/05/14)

    The invention mainly solves the problems...

    METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND

    -

    Paragraph 0122-0166, (2019/09/06)

    Provided is a method for producing an al...

    PROCESS FOR PREPARING AN ALKENYLPHOSPHONIC ACID DERIVATIVE

    -

    Page/Page column 6, (2010/06/11)

    Process for preparing an alkenylphosphon...

    4645-32-3 Process route

    Dimethyl phosphite
    868-85-9

    Dimethyl phosphite

    acetylene
    74-86-2,25067-58-7

    acetylene

    dimethylvinylphosphonate
    4645-32-3

    dimethylvinylphosphonate

    Conditions
    Conditions Yield
    Dimethyl phosphite; With 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,3-bis-(diphenylphosphino)propane; nickel(II) acetate tetrahydrate; at 95 ℃; for 0.166667h;
    acetylene; at 100 ℃; for 1.5h; under 760.051 Torr; Product distribution / selectivity;
    87%
    bis(acetylacetonate)nickel(II); 1,3-bis-(diphenylphosphino)propane; triphenylphosphine; In tetraethyleneglycol-dimethylether; at 100 ℃; for 1.66667h; under 760.051 Torr; Product distribution / selectivity;
    80%
    bis(acetylacetonate)nickel(II); 1,3-bis-(diphenylphosphino)propane; In tetraethyleneglycoldimethylether; at 100 ℃; for 1.66667h; Product distribution / selectivity;
    70%
    With cerium(IV) oxide; palladium(II) nitrate dihydrate; nitric acid; In tetrahydrofuran; water; at 120 ℃; for 4h; under 15001.5 Torr; Reagent/catalyst; Temperature; Pressure; Autoclave; Inert atmosphere;
    53%
    With phosphonic Acid; tetrakis(trimethylphosphine)nickel(0); In toluene; at 0 ℃; for 5h; under 150.015 Torr; Reagent/catalyst; Concentration; Pressure; Temperature; Catalytic behavior; Autoclave;
    acetylene
    74-86-2,25067-58-7

    acetylene

    dimethylvinylphosphonate
    4645-32-3

    dimethylvinylphosphonate

    Conditions
    Conditions Yield
    In n-octyne;
    92%
    In n-octyne;
    85%

    4645-32-3 Upstream products

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      67-56-1

      methanol

    • 1438-74-0
      1438-74-0

      vinyldichlorophosphine oxide

    • 26119-41-5
      26119-41-5

      dimethyl 2-chloroethylphosphonate

    • 106-93-4
      106-93-4

      ethylene dibromide

    4645-32-3 Downstream products

    • 88691-17-2
      88691-17-2

      (2-Chloro-1-phenylsulfanyl-ethyl)-phosphonic acid dimethyl ester

    • 185897-11-4
      185897-11-4

      (2-{(2-{Bis-[2-(dimethoxy-phosphoryl)-ethyl]-phosphanyl}-phenyl)-[2-(dimethoxy-phosphoryl)-ethyl]-phosphanyl}-ethyl)-phosphonic acid dimethyl ester

    • 131486-53-8
      131486-53-8

      cis-<2-Methoxy-2-(2-phenylethenyl)cyclopropyl>phosphonsaeure-dimethylester

    • 131407-55-1
      131407-55-1

      trans-<2-Methoxy-2-(2-phenylethenyl)cyclopropyl>phosphonsaeure-dimethylester

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