Ibuprofen
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Product Name :
Ibuprofen
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CAS No :
15687-27-1
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Project State :
Commercial
Application
General Description
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What is the Ibuprofen ?
Ibuprofen is Colourless, crystalline solid, while it's Molecular Formula is C13H18O2. Antibiotic
What is the CAS number for Ibuprofen ?
The CAS number of Ibuprofen is 15687-27-1.
More information of Ibuprofen 15687-27-1 are:
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Synonyms |
Benzeneacetic acid, .alpha.-methyl-4- (2-methylpropyl)-;2-(4-Isobutylphenyl)propanoic acid;(.+ -.)-2-(p-Isobutylphenyl)propionic acid;Benzeneacetic acid,R-methyl-4-(2-methylpropyl)-;2-(4-Isobutylphenyl)propionic Acid;Motrin;(2RS)-2-[4-(2-methylpropyl)phenyl]propanoic acid;(4-Isobutylphenyl)-alpha-methylacetic acid;(+-)-ibuprofen;(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid; |
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CAS Number |
15687-27-1 |
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Molecular Formula |
C13H18O2 |
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Molecular Weight |
206.285 |
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Density |
1.029 g/cm3 |
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Melting Point |
77-78 °C(lit.) |
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Boiling Point |
319.6 °C at 760 mmHg |
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Flash Point |
216.7 °C |
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HS CODE |
2916.39 |
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PSA |
37.30000 |
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LogP |
3.07320 |
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Pka |
pKa 4.45± 0.04(H2O,t = 25±0.5,I=0.15(KCl))(Approximate) |
What is Ibuprofen (15687-27-1) used for?
Ibuprofen is a white, crystalline anti-infl ammatory drug used in numerous medications. It is the active ingredient marketed under various trade names including Advil, Motrin, and Nurofen. Ibuprofen is a nonsteroidal anti-infl ammatory drug (NSAID) used as a pain reliever (analgesic), fever reducer (antipyretic), and inflammation reducer. Infl ammation is a general physiological response to tissue damage characterized by swelling, pain, and heat.Ibuprofen works by inhibiting the enzyme cyclooxygenase (COX), which in turn interferes with the synthesis of prostaglandins. COX exists as several coenzyme forms that are similar in structure: COX-1, COX-2, COX-3; ibuprofen is a nonselective inhibitor of both COX-1 and COX-2. COX-1 is continually produced in mammalian cells throughout the body in response to physiological stimuli. It is responsible for the production of prostaglandins, which get their name because it was originally believed they were synthesized in the prostate gland. In fact, prostaglandins are synthesized throughout the body and act like hormones by stimulating action in target cells. Prostaglandins, which are fatty acid compounds consisting of a 20-carbon chain including a 5 carbon ring, are involved in numerous physiological processes including renal function, blood clotting, and stomach mucus production. COX-2 is synthesized only in specifi c parts of the body (kidneys, brain, trachea) as needed and is therefore called an induced enzyme. COX-2 produces prostaglandins in response to tissue damage and infl ammation. Infl ammatory prostaglandins produce swelling, pain, and fever.
InChI:InChI=1/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/p-1/t10-/m1/s1
Articles related to Ibuprofen:
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Article |
Source |
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A NOVEL SYNTHESIS OF α,β-UNSATURATED NITRILES FROM AROMATIC KETONES VIA CYANOPHOSPHATES |
Harusawa, Shinya,Yoneda, Ryuji,Kurihara, Takushi,Hamada, Yasumasa,Shioiri, Takayuki , p. 427 - 428 (1984) |
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The continuous-flow synthesis of ibuprofen |
Bogdan, Andrew R.,Poe, Sarah L.,Kubis, Daniel C.,Broadwater, Steven J.,McQuade, D. Tyler , p. 8547 - 8550 (2009) |
How to get the best price on Ibuprofen?
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