Mafenide hydrochloride
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Product Name :
Mafenide hydrochloride
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CAS No :
138-37-4
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Project State :
Commercial
Application
General Description
Manufacturers supply cost-effective and customizable Mafenide hydrochloride 138-37-4
- Molecular Formula:C7H10N2O2S.HCl
- Molecular Weight:222.696
- Melting Point:261-263 °C(lit.)
- Boiling Point:382 °C at 760 mmHg
- Flash Point:184.8 °C
- PSA：94.56000
- LogP:3.07610
Mafenide hydrochloride(Cas 138-37-4) Usage
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Purification Methods |
Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.] |
InChI:InChI=1/C7H10N2O2S.2ClH/c8-5-6-1-3-7(4-2-6)12(9,10)11;;/h1-4H,5,8H2,(H2,9,10,11);2*1H
138-37-4 Process route
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138-37-4
mafenide hydrochloride
| Conditions | Yield |
|---|---|
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N-Benzyliden-p-aminomethyl-benzolsulfonamid (XVIII), 36percentig. HCl;
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85-44-9
phthalic anhydride
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138-37-4
mafenide hydrochloride
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7518-98-1
4-phthalimidomethyl-benzenesulfonamide
| Conditions | Yield |
|---|---|
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In
N,N-dimethyl-formamide;
Reflux;
Alkaline conditions;
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138-37-4 Downstream products
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24489-26-7
5-methyl-isoxazole-3-carboxylic acid 4-sulfamoyl-benzylamide
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24488-85-5
3-methyl-isoxazole-5-carboxylic acid 4-sulfamoyl-benzylamide
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33645-55-5
L-2-Carbobenzoxyamino-2-carbethoxyethan-N-homosulfanilylamidosulfonamid
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928211-28-3
5-(4-Sulfamoyl-benzylcarbamoyl)-pentanoic acid methyl ester