Pharmaceutial Intermediates
  • METHYL TRIFLUOROPYRUVATE

    • Product Name   :   

      METHYL TRIFLUOROPYRUVATE

    • CAS No   :   

      13089-11-7

    • Project State   :   

      Commercial

    Application

    General Description

    Cost-effective and customizable METHYL TRIFLUOROPYRUVATE 13089-11-7 supplier

    • Molecular Formula:C4H3F3O3
    • Molecular Weight:156.061
    • Appearance/Colour:clear colorless to light yellow liquid 
    • Melting Point:84-86 °C 
    • Refractive Index:n20/D 1.332(lit.)  
    • Boiling Point:58.5 °C at 760 mmHg 
    • Flash Point:80 °F 
    • PSA:43.37000 
    • Density:1.398 g/cm3 
    • LogP:0.29080 

    13089-11-7 Relevant articles

    Green synthesis of methyl trifluoropyruvate catalyzed by solid acids

    Lermontov, Sergey A.,Ushakova, Lyudmila L.,Kuryleva, Nina V.

    , p. 332 - 334 (2008)

    Solid acids - NiSO4/Al2O3, Fe2(SO4)3/Al2...

    Methyl 3,3,3-trifluoropyruvate: An improved procedure starting from hexafluoropropene-1,2-oxide; identification of byproducts

    Dolensky, Bohumil,Kví?ala, Jaroslav,Pale?ek, Ji?í,Paleta, Old?ich

    , p. 67 - 74 (2007/10/03)

    Optimized laboratory-scale preparation o...

    UNUSUAL REACTION CHEMISTRY IN THERMAL DECOMPOSITION OF ALKALI METAL 2-ALKOXY-2,3,3,3-TETRAFLUOROPROPIONATE SALTS

    Pellerite, Mark J.

    , p. 43 - 66 (2007/10/02)

    Pyrolyses of several salts ROCF(CF3)CO2(...

    ALKOXYPENTAFLUOROACETONES

    Bloshchitsa, F. A.,Burmakov, A. I.,Kunshenko, B. V.,Alekseeva, L. A.,Yugupol'skii, L. M.

    , p. 1563 - 1564 (2007/10/02)

    -

    13089-11-7 Process route

    2-fluoro-2-methoxy trifluoropropanoic acid methyl ester
    10186-63-7

    2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

    methyl 3,3,3-trifluoropyruvate
    13089-11-7

    methyl 3,3,3-trifluoropyruvate

    methyl 3,3,3-trifluoro-2-hydroxy-2-methoxypropanoate
    19607-21-7

    methyl 3,3,3-trifluoro-2-hydroxy-2-methoxypropanoate

    Conditions
    Conditions Yield
    With sulfuric acid; silica gel; at 125 ℃; for 0.5h;
    94.5%
    2-fluoro-2-methoxy trifluoropropanoic acid methyl ester
    10186-63-7

    2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

    trifluoroacetic acid-methyl ester
    431-47-0

    trifluoroacetic acid-methyl ester

    methyl 3,3,3-trifluoropyruvate
    13089-11-7

    methyl 3,3,3-trifluoropyruvate

    methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate
    19390-75-1

    methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate

    Conditions
    Conditions Yield
    With sulfuric acid; silica gel; at 140 ℃;
    12%
    14%
    46%

    13089-11-7 Upstream products

    • 10186-63-7
      10186-63-7

      2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

    • 67-56-1
      67-56-1

      methanol

    • 428-59-1
      428-59-1

      Hexafluoropropene oxide

    • 123202-05-1
      123202-05-1

      Sodium; 2,3,3,3-tetrafluoro-2-methoxy-propionate

    13089-11-7 Downstream products

    • 126956-18-1
      126956-18-1

      N-methyl-2-(1-methoxycarbonyl-1-hydroxy-2,2,2-trifluoroethyl)pyrrole

    • 132145-24-5
      132145-24-5

      methyl 2-benzoylimino-3,3,3-trifluoropropionate

    • 136308-19-5
      136308-19-5

      4-Cyclohexylidene-2-hydroxy-2-trifluoromethyl-butyric acid methyl ester

    • 117015-45-9
      117015-45-9

      methyl ester of 2-hydroxy-2-trifluoromethyl-4-pentenoic acid

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