Pharmaceutial Intermediates
  • 4-Hydroxy-2-butanone

    • Product Name   :   

      4-Hydroxy-2-butanone

    • CAS No   :   

      590-90-9

    • Project State   :   

      Commercial

    General Description

    Buy high quality and low price 4-Hydroxy-2-butanone 590-90-9 now

    • Molecular Formula:C4H8O2
    • Molecular Weight:88.1063
    • Appearance/Colour:Colorless liquid 
    • Vapor Pressure:1.05mmHg at 25°C 
    • Melting Point:15°C (estimate) 
    • Refractive Index:1.430 
    • Boiling Point:156.3 °C at 760 mmHg 
    • PKA:14.43±0.10(Predicted) 
    • Flash Point:55.5 °C 
    • PSA:37.30000 
    • Density:0.987 g/cm3 
    • LogP:-0.04220 

    4-Hydroxy-2-butanone(Cas 590-90-9) Usage

    Definition

    ChEBI: A beta-hydroxy ketone that is butan-2-one substituted by a hydroxy group at position 4.

    General Description

    4-Hydroxy-2-butanone is an important pharmaceutical intermediate. Gas phase reaction of the OH radicals with 4-hydroxy-2-butanone has been investigated by absolute rate method.

    InChI:InChI=1/C4H8O2/c1-4(6)2-3-5/h5H,2-3H2,1H3

    590-90-9 Relevant articles

    Chemoselective Oxidation of Secondary Hydroxy Groups by the Molybdenum Hexacarbonyl/Cetylpyridinium Chloride/t-Butyl Hydroperoxide System

    Yamawaki, Kazumasa,Yoshida, Tsutomu,Suda, Takashi,Ishii, Yasutaka,Ogawa, Masaya

    , p. 59 - 60 (1986)

    The system molybdenum hexacarbonyl/cetyl...

    Enzymatic syntheses of 13C-enriched geranylgeranyl diphosphate and casbene from 13C-labeled isopentenyl diphosphate

    Huang, Qiulong,Huang, Kexue,Scott

    , p. 2033 - 2036 (1998)

    Geranylgeranyl diphosphate and casbene w...

    HIGHLY SELECTIVE OXIDATION OF SECONDARY HYDROXYL FUNCTIONS USING THE VO(acac)2-t-BuOOH SYSTEM

    Kaneda, Kiyotomi,Kawanishi, Yasuyuki,Jitsukawa, Koichiro,Teranishi, Shiichiro

    , p. 5009 - 5010 (1983)

    The VO(acac)2-t-BuOOH system shows high ...

    Process for preparing 4-hydroxy-2-butanone

    -

    Paragraph 0024-0044, (2020/12/31)

    The invention provides a process for pre...

    Hydroxycarbonyl compound (by machine translation)

    -

    Paragraph 0070, (2020/01/31)

    After the separated and purified efficie...

    Preparation method of hydroxyl ketone compound

    -

    Paragraph 0024-0036; 0039-0048; 0055-0059, (2020/07/12)

    The invention discloses a preparation me...

    Reductive Electrochemical Activation of Molecular Oxygen Catalyzed by an Iron-Tungstate Oxide Capsule: Reactivity Studies Consistent with Compound i Type Oxidants

    Bugnola, Marco,Shen, Kaiji,Haviv, Eynat,Neumann, Ronny

    , p. 4227 - 4237 (2020/05/05)

    The reductive activation of molecular ox...

    590-90-9 Process route

    1.3-butanediol
    18826-95-4,107-88-0

    1.3-butanediol

    methanol
    67-56-1

    methanol

    2-hydroxy-3-butene
    598-32-3

    2-hydroxy-3-butene

    ethanol
    64-17-5

    ethanol

    (E/Z)-2-buten-1-ol
    6117-91-5,542-72-3

    (E/Z)-2-buten-1-ol

    1-Hydroxy-3-butanone
    590-90-9

    1-Hydroxy-3-butanone

    acetaldehyde
    75-07-0,9002-91-9

    acetaldehyde

    methyl vinyl ketone
    78-94-4,25038-87-3

    methyl vinyl ketone

    acetone
    67-64-1

    acetone

    butanone
    78-93-3

    butanone

    iso-butanol
    78-92-2,15892-23-6

    iso-butanol

    butan-1-ol
    71-36-3

    butan-1-ol

    Conditions
    Conditions Yield
    In neat (no solvent, gas phase); under 759.826 Torr;
    ethanol
    64-17-5

    ethanol

    pentanal
    110-62-3

    pentanal

    1-Hydroxy-3-butanone
    590-90-9

    1-Hydroxy-3-butanone

    acetaldehyde
    75-07-0,9002-91-9

    acetaldehyde

    2-Pentanone
    107-87-9

    2-Pentanone

    ethyl acetate
    141-78-6

    ethyl acetate

    butanoic acid ethyl ester
    105-54-4

    butanoic acid ethyl ester

    acetone
    67-64-1

    acetone

    butanone
    78-93-3

    butanone

    butan-1-ol
    71-36-3

    butan-1-ol

    1,2-dihydroxybutane
    584-03-2

    1,2-dihydroxybutane

    Conditions
    Conditions Yield
    With MgO/Cu; at 300 ℃; for 4h;

    590-90-9 Upstream products

    • 75-21-8
      75-21-8

      oxirane

    • 75-07-0
      75-07-0

      acetaldehyde

    • 689-97-4
      689-97-4

      3-buten-1-yne

    • 18826-95-4
      18826-95-4

      1.3-butanediol

    590-90-9 Downstream products

    • 20705-59-3
      20705-59-3

      4-(tetrahydropyran-2-yloxy)butan-2-one

    • 10150-87-5
      10150-87-5

      1-acetoxybutan-3-one

    • 2568-33-4
      2568-33-4

      3-methyl-butane-1,3-diol

    • 1192-42-3
      1192-42-3

      4,5-dihydro-3-hydroxy-3-methyl-2(3H)-furanone

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