Pharmaceutial Intermediates
  • Acetylacetaldehyde dimethyl acetal

    • Product Name   :   

      Acetylacetaldehyde dimethyl acetal

    • CAS No   :   

      5436-21-5

    • Project State   :   

      Commercial

    Application

    General Description

    High quality purity >99% Acetylacetaldehyde dimethyl acetal 5436-21-5 for sale

    • Molecular Formula:C6H12O3
    • Molecular Weight:132.159
    • Appearance/Colour:Clear colorless to yellow liquid 
    • Vapor Pressure:1.35mmHg at 25°C 
    • Melting Point:-82 °C 
    • Refractive Index:n20/D 1.414(lit.)  
    • Boiling Point:172.1 °C at 760 mmHg 
    • Flash Point:49.4 °C 
    • PSA:35.53000 
    • Density:0.959 g/cm3 
    • LogP:0.58440 

    Acetylacetaldehyde dimethyl acetal(Cas 5436-21-5) Usage

    Synthesis Reference(s)

    The Journal of Organic Chemistry, 41, p. 3765, 1976 DOI: 10.1021/jo00885a028Tetrahedron Letters, 28, p. 6657, 1987 DOI: 10.1016/S0040-4039(00)96938-7

    General Description

    4,4-Dimethoxy-2-butanone (Acetylacetaldehyde dimethylacetal) is a ketone.

    InChI:InChI=1/C6H12O3/c1-5(7)4-6(8-2)9-3/h6H,4H2,1-3H3

    5436-21-5 Relevant articles

    Biosynthesis of polyketide-terpenoid (Meroterpenoid) metabolites andibenin B and andilesin A in aspergillus variecolor

    Simpson, Thomas J.,Anmed, Salman A.,McIntyre, C. Rupert,Scott, Fiona E.,Sadler, Ian H.

    , p. 4013 - 4034 (1997)

    Incorporation of 13C-labelled acetates a...

    Synthesis method of 4,4-dimethoxy-2-butanone

    -

    Paragraph 0017-0037, (2021/11/06)

    The invention discloses a synthesis meth...

    Electronic Asymmetry of an Annelated Pyridyl-Mesoionic Carbene Scaffold: Application in Pd(II)-Catalyzed Wacker-Type Oxidation of Olefins

    Bera, Jitendra K.,Dutta, Indranil,Kunnikuruvan, Sooraj,Reshi, Noor U Din,Saha, Sayantani,Yadav, Suman

    , p. 11385 - 11393 (2020/11/23)

    The two donor modules of an annelated py...

    CuII-Catalyzed Oxidative Formation of 5-Alkynyltriazoles

    Liu, Peiye,Brassard, Christopher J.,Lee, Justin P.,Zhu, Lei

    supporting information, p. 380 - 390 (2020/01/24)

    In an alcoholic solvent under the cataly...

    New process for preparing pyrazole carboxylic acid derivatives

    -

    Paragraph 0047; 0065-0070, (2017/04/03)

    The present invention relates to a metho...

    5436-21-5 Process route

    3-butenal dimethyl acetal
    72380-56-4

    3-butenal dimethyl acetal

    acetylacetaldehyde dimethyl acetal
    5436-21-5

    acetylacetaldehyde dimethyl acetal

    Conditions
    Conditions Yield
    With tert.-butylhydroperoxide; C21H19N5Pd(2+)*2BF4(1-); In decane; acetonitrile; at 70 ℃; for 24h; Temperature;
    95%
    sodium methylate
    124-41-4

    sodium methylate

    acetone
    67-64-1

    acetone

    formic acid ethyl ester
    109-94-4

    formic acid ethyl ester

    acetylacetaldehyde dimethyl acetal
    5436-21-5

    acetylacetaldehyde dimethyl acetal

    Conditions
    Conditions Yield
    With sulfuric acid; at 0 - 50 ℃; for 2h; Temperature;
    73.2%

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