3-Chloro-5-methylaniline
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Product Name :
3-Chloro-5-methylaniline
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CAS No :
29027-20-1
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Project State :
Commercial
Application
General Description
3-Chloro-5-methylaniline 29027-20-1 with purity >99% Low price in stock
- Molecular Formula:C7H8ClN
- Molecular Weight:141.6
- Boiling Point:248.6±20.0℃ (760 Torr)
- PKA:3.66±0.10(Predicted)
- Flash Point:104.1±21.8℃
- PSA：26.02000
- Density:1.180±0.06 g/cm3 (20 oC 760 Torr)
- LogP:2.81180
29027-20-1 Relevant articles
Ligand Promoted meta-C-H Chlorination of Anilines and Phenols
Shi, Hang,Wang, Peng,Suzuki, Shin,Farmer, Marcus E.,Yu, Jin-Quan
, p. 14876 - 14879 (2016)
Pd-catalyzed meta-C-H chlorination of an...
Fe2O3/NGr@C- and Co-Co3O4/NGr@C-catalysed hydrogenation of nitroarenes under mild conditions
Formenti, Dario,Topf, Christoph,Junge, Kathrin,Ragaini, Fabio,Beller, Matthias
, p. 4473 - 4477 (2016/07/06)
An improved hydrogenation of nitroarenes...
FACTOR IXA INHIBITORS
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Page/Page column 41, (2016/11/07)
The present invention provides a compoun...
IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR
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Paragraph 00358, (2013/06/27)
Compounds, compositions, and methods for...
29027-20-1 Process route
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16582-38-0
3-chloro-5-nitrotoluene
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29027-20-1
3-chloro-5-methylaniline
| Conditions | Yield |
|---|---|
|
With
tin(II) chloride dihdyrate;
In
ethanol;
for 3h;
Reflux;
|
97% |
|
With
tin(II) chloride dihdyrate; ethanol;
for 3h;
Reflux;
|
97% |
|
With
tin(ll) chloride;
In
ethanol;
for 3h;
Heating;
|
93% |
|
3-chloro-5-nitrotoluene;
With
tin(IV) chloride;
In
ethanol;
at 4 - 20 ℃;
for 4h;
With
sodium hydroxide;
In
ethanol; water;
at 0 ℃;
|
80% |
|
3-chloro-5-nitrotoluene;
With
tin(ll) chloride;
In
ethanol;
for 3h;
With
sodium hydroxide; water;
|
80% |
|
With
hydrogenchloride; tin;
|
|
|
With
hydrogenchloride; tin(ll) chloride;
Multistep reaction;
|
|
|
bei der Reduktion;
|
|
|
|
|
|
bei der Reduktion;
|
|
|
With
hydrogen;
In
ethanol; water;
at 70 ℃;
for 20h;
under 15001.5 Torr;
Reagent/catalyst;
Autoclave;
|
|
|
With
ethanol; tin(IV) chloride;
at 85 ℃;
for 2h;
|
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5465-33-8
2-chloro-4-methyl-6-nitroaniline
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29027-20-1
3-chloro-5-methylaniline
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1.1: sulfuric acid; aq. sodium nitrite / ethanol / 0.5 h / 0 - 20 °C
1.2: 69 percent / ethanol; H2O / Heating
2.1: 93 percent / tin(II) chloride dihydrate / ethanol / 3 h / Heating
With
sulfuric acid; tin(ll) chloride; sodium nitrite;
In
ethanol;
|
29027-20-1 Upstream products
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16582-38-0
3-chloro-5-nitrotoluene
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5465-33-8
2-chloro-4-methyl-6-nitroaniline
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89-62-3
4-methyl-2-nitroaniline
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618-85-9
3,5-dinitrotoluene
29027-20-1 Downstream products
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56978-43-9
N-(3-chloro-5-methylphenyl)acetamide
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40233-54-3
3-chloro-5,N,N-trimethyl-aniline
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471909-97-4
3-chloro-5-methyl-phenyl isothiocyanate
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74875-47-1
2-Chloro-N-(3-chloro-5-methyl-phenyl)-4-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-benzenesulfonamide